Approved vaccines for infants to protect against a serious respiratory disease called RSV are getting new scrutiny from federal health agency officials, according to Reuters. Heightened federal scrutiny adds uncertainty for RSV manufacturers at a time when the childhood vaccine environment is already polarized.
Structure Therapeutics’ experimental obesity pill led to an average 12.1% weight loss after 36 weeks on a 120 mg daily dose, which stacks up well against competitors. Newcomers to the weight loss drug market still face key disadvantages, even with strong trial results. For smaller weight loss drug developers that may not have the risk appetite or resources to compete with larger players, the best way to cash in on a market dominated by two giants may be to pursue a partnership or acquisition.
More than half (54%) of US adults have heard about TrumpRx, but only 20% know what the administration’s planned website for direct-to-consumer drugs is about, per a recent BuzzRx report. Pharma companies see TrumpRx as a new way to reach consumers directly, but public awareness of the upcoming platform remains low.
Sell-side platform PubMatic and connected TV (CTV) ad company BrightLine announced a partnership that will bring addressable and interactive CTV ad formats to PubMatic’s programmatic platform. As interactivity becomes a critical differentiator in a crowded CTV ad landscape, marketers can use PubMatic and BrightLine’s partnership to more easily deploy interactive CTV ad formats across major publishers.
Podcast TV attention metrics (AUs) held steady from Q3 2024 to Q3 2025 even as streaming audio AUs declined, per our industry KPI data provided by Adelaide. Podcasts held a 6 to 8 point advantage over streaming audio in every quarter, fluctuating slightly between 47.4 and 50.1 AUs. Streaming audio AUs dipped from 44.1 to 41.8, a 5.2% YoY decline. Podcasts offer a unique combination of engagement and competitive CPMs. Use the format to capitalize on high-attention placements, trust in ads and host recommendations, and mid-funnel potential.
Meta is restructuring its European ad system under pressure from the Digital Markets Act (DMA), setting up one of the most consequential shifts to its ad targeting model in a decade, per The Economic Times. Users can opt to allow full data sharing for personalized ads or limit data sharing and receive a lighter, less-tailored ad experience. Brands reliant on Meta or those that have deep EU campaigns should diversify targeting inputs, invest in creative that performs without deep personalization, and build measurement strategies resilient to thinner data signals.
Yelp’s newest Most Loved Brands list identifies which national chains consumers returned to most in a year defined by cautious, value-sensitive spending. Unlike perception-based rankings, Yelp’s loyalty score draws from behavioral signals—repeat visits to brand pages, review volume, sentiment, and photo activity—revealing what people actually do, not just what they say. Dave’s Hot Chicken leads the list on the strength of customizable experiences and overwhelmingly positive ratings, while legacy chains, nostalgia-driven brands, and Zillennial favorites succeed for distinct reasons. For marketers, the findings echo broader path-to-purchase trends: consumers increasingly depend on reviews, consistency, and social proof to validate where they spend.
Uber is offering customer data to marketers to enhance ad targeting and placement capabilities. The data is available through Uber Intelligence, its new insights platform powered by LiveRamp. Advertisers can get information on how people “move, dine, travel, and order” to build a better understanding of customers’ behavior patterns, the company said in a blog post. Marketers should experiment with Uber Intelligence’s insights to create bespoke ad strategies that segment audiences, identify relevant customers, and personalize targeting.
Mobile advertising remains concentrated around a few dominant platforms, but challengers are gaining ground, per AppsFlyer’s Performance Index. Worldwide, Google Ads and Apple Ads remain No. 1 and No. 2, respectively, but AppLovin, Mintegral, Meta Ads, and TikTok for Business are climbing the rankings. As industries push further into mobile ads, competition is intensifying around creative efficiency, privacy-safe measurement, and cross-platform diversification. Marketers should prioritize mobile-first creative, test emerging networks early, and diversify across iOS and Android to hedge volatility.
2026 is set to be another strong year for the global travel industry. A record 5.2 billion people are expected to travel by air, up 4.4% YoY, according to the IATA. While global demand remains robust, the US industry is contending with several headwinds, including weakening interest in domestic travel—from both US consumers as well as international visitors—which is pressuring budget carriers and pushing prices upward as airlines target premium customers. With the softening jobs market and growing uncertainty contributing to consumers’ “bad vibes” about the economy and their personal finances, US demand for travel is likely to continue to be uneven in 2026.
On today’s podcast episode, we discuss how LGBTQ+ streaming platform Revry has been able to gain traction in a crowded, highly competitive streaming TV universe; what advertisers misunderstand about marketing to the queer community; and some examples of when queer representation in media hit the nail on the head—and when it missed the mark. Join Senior Director of Podcasts and host Marcus Johnson, along with analysts Paola Flores-Marquez and Emmy Liederman, and Revry CEO and Co-Founder Damian Pelliccione. Listen everywhere, and watch on YouTube and Spotify.
The US accounts for just 10% of TikTok users but generates 41% of the platform's ad revenue worldwide, according to a July forecast from EMARKETER.
While commerce media networks expand, retailers can take advantage of the efficiencies and measurement capabilities that they can provide.Retail media networks alone are expected to claim one-fifth of US digital ad spending by 2029, according to EMARKETER’s September forecast.
The commerce media landscape is bracing for a defining year. Pressure is building across retailers and platforms to rethink how shoppers discover, evaluate, and buy products.
In their earnings last week, Royal Bank of Canada (RBC) and TD Bank—Canada’s two largest financial institutions—flagged investments in AI R&D. This builds on recent data about banks’ deployment of agentic AI as well as detailed insights from JPMorgan’s and Bank of America’s public statements about their massive spending on AI and supporting infrastructure. Dollars spent on technology matter—so do how the money is spent and the number and severity of conflicting priorities. Business troubles are metastasizing more quickly because of the rapid pace of change technological innovation is imposing on a historically staid industry.
e news: Multicultural consumers—a segment whose buying power has grown 345% over the last 20 years—now expect brands to prioritize representation in ads, per a Snapchat study. Brands must tailor ad strategies to appeal to multicultural consumers, but should understand that simple, one-off campaign inclusion won’t be enough to drive action.
The rise of AI browsers like OpenAI’s Atlas and Perplexity’s Comet is setting up a possible bifurcation of the web. These agent-driven browsers navigate pages, click through tasks, and fetch information on a user’s behalf while traditional browsers anchor the search-centric behaviors most people rely on. The divergence could result in further fragmentation where there are two versions of websites. Brands that structure their content for both—with product metadata, clear semantic HTML, and agent-ready pages focused on specs, summaries, and FAQs—will have a higher chance of visibility across browsers.
US ad spend growth will grow a total of 11% in 2025, excluding political spending, per an updated Madison & Wall forecast cited by Mediapost. The figure is well above Madison & Wall’s previous estimate of 3.6% growth and follows 13% YoY growth in Q3. Even as total media ad spending continues to grow, growth doesn’t entirely negate the overall climate of uncertainty that will undoubtedly affect the ad industry in the year ahead. Slowing growth expected from Madison & Wall in 2026 and ongoing economic headwinds indicate that advertisers are still operating in an era of caution.
Retailers experimenting with agentic AI are doing so with commercial urgency, not curiosity. In an EMARKETER interview, Criteo’s Michael Greene said retailers now see onsite AI as “mission critical” for owning the shopping journey—especially as consumers increasingly use chat-based tools for early discovery. Generic LLMs lack real retail signals like inventory, regional availability, and nuanced category expertise, making proprietary data the retailer’s strongest edge. With Gen Z already leaning heavily on AI for purchase research, retailers must build systems that deliver more relevant, trustworthy guidance than general chat interfaces. The mandate is clear: build AI that improves baskets, conversion, and shopper retention.
L’Oréal is doubling its stake in cosmetic injectables company Galderma to 20%, the company said, as it looks to expand in the fast-growing aesthetics market and support growth amid global headwinds. While some competitors retrench, L’Oréal is pursuing acquisitions in categories like fragrance and haircare with the strongest growth potential. L'Oréal's moves reflect the shifts in consumer beauty spending. Resilient demand for self-care, wellness, and premium products is fueling growth in fragrances and haircare, while K-beauty is gaining traction as consumers search for affordable and effective skincare products.