The news: Rare disease drugmaker Sarepta Therapeutics is pausing sales of a muscular dystrophy drug, Elevidys, after initially refusing an FDA request to halt sales due to safety concerns. The takeaway: Elevydis’ path to FDA approval was unconventional, but deemed appropriate at the time for a devastating disease. The new deaths and now paused sales serve as caution for both the FDA and drugmakers to balance the emotional sway of unmet medical needs with complete and continued clinical research.

The news: Insurance premiums are set to rise by 15% next year for the people who buy through the Affordable Care Act, per a new KFF analysis. Our take: While the Trump administration is eliminating the ACA tax credits, states where the president won the election account for 88% of ACA enrollment growth since 2020, per KFF research in April. When premium increases roll out across the ACA marketplace, and spillover into higher costs for hospitals and healthcare services, we expect plenty of political finger-pointing over fault, but little agreement on ways to improve US healthcare and keep consumers out of medical debt.

The trend: People who actively use patient portals are less likely to skip an upcoming doctor’s appointment than those without portal accounts, according to recent research from Epic that analyzed 1.6 billion visits in 2024. Our take: Engaging with a patient portal is important, but it isn’t a major needle mover for appointment no-shows. Strategies such as helping coordinate transportation, sending text and email alerts, and communicating no-show fees could play a bigger role in eliminating costly no-shows.

The news: Abbott and Johnson & Johnson reported lower-than-expected costs from tariffs during Q2 earnings this week. Our take: It seemed like medical device companies would be the hardest hit by tariffs initially. So the positive spin from Abbott and J&J is encouraging. But tariffs are still costly. While device and diagnostic companies talk broadly about plans to mitigate tariff effects, raising prices for healthcare systems and consumers isn’t off the table.

The news: An FDA panel endorsed the removal of black box warnings on hormone therapies used for menopause. For context: Black box warnings are the strongest safety warning issued by the FDA for Rx drugs and highlight serious or life-threatening risks. Our take: Removing the black box warning could encourage pharma brands to not only develop more treatments but also market hormone therapy more. While personal risks and benefits still need to be weighed with a doctor, the change may result in more women on treatment.

The news: Pfizer and Bristol Myers Squibb will launch a direct-to-patient channel to sell their blockbuster blood thinner Eliquis at a reduced cash-pay price. Our take: Pfizer and Bristol Myers Squibb have anticipated the Eliquis patent loss and sales drop for years as part of the typical branded drug cycle. We see the new direct sales platform launch not as a play for new revenues, but rather a negotiating nod to the Trump administration. Only 10% of Eliquis patients are uncovered by insurance, so it’s a small market to court as a revenue-driving ploy. However, Trump has made it clear he’s open to using any levers possible to force lower drug prices, pushing pharma companies to offer good faith options and concessions.

The news:. A new report reviewed by STAT reveals that Pfizer and Eli Lilly pay their telehealth provider partners upwards of a few million dollars. Our take: Drugmakers in the D2C telehealth market likely won’t be too worried about the report’s findings. It will be difficult for regulators to prove that a pharma company’s payment to a telehealth partner is directly tied to prescription volume. Drug brands will need to boost awareness of their D2C offerings to justify the price they pay telehealth firms, however.