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Doctors begin to lose interest in Rx medicines months before prescribing slows

The news: Doctors started paying more attention to information and ads for new weight loss drugs months before they began prescribing them, according to research from ZoomRx. The study tracked obesity health-related web browsing and ad exposures for 279 healthcare providers on digital channels and 204 on TV and connected TV.

Digging into the details: The research tracked doctors’ attention to GLP-1 obesity drugs Wegovy (Novo Nordisk) and Zepbound (Eli Lilly) for more than a year, from Q2 2024 through Q1 2025.

  • Physician engagement with content and advertising about Wegovy began to decline in Q3 2024.
  • Doctors began to pay more attention to Lilly’s Zepbound content and advertising on digital channels and connected TV (CTV). By the end of 2024, Zepbound grew from 0% to a 20% share of physicians’ attention in obesity drugs.

Zooming out: According to ZoomRx, when doctors started paying more attention to Zepbound content and ads, it was an early sign that its sales would soon increase.

  • Even though doctors' attention shifted from Wegovy to Zepbound in late 2024, Wegovy's sales still peaked at $2.8 billion in the last quarter of that year.
  • Just six months later, Zepbound's sales climbed to $2.3 billion in the first quarter of 2025, showing that doctors' early interest was a good predictor of its future success.

Why it matters: Traditional data measurements like the number of prescriptions and quarterly sales lag behind more predictive behavioral actions like changes in prescribers’ interest.

Especially for new drug classes like GLP-1s, tracking physicians’ journeys as they learn the science, dosing, and patient appropriateness can create a window of opportunity for drugmakers to shape prescribing habits.

Our take: Pharma companies need to find where doctors are searching or reading about Rx drugs and how their interest in a drug’s information is changing, even before the sales numbers are in.

  • Track Reddit forums and physician social media channels like Sermo and Doximity to gauge behaviors and attitudes and shift marketing plans to meet them.
  • Use sales reps and peer-led webinars to capture early interest—and keep refreshing that marketing with updated data and patient results as competing entrants begin to pull attention away.

This content is part of EMARKETER’s subscription Briefings, where we pair daily updates with data and analysis from forecasts and research reports. Our Briefings prepare you to start your day informed, to provide critical insights in an important meeting, and to understand the context of what’s happening in your industry. Not a subscriber? Click here to get a demo of our full platform and coverage.

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